工具类服务
编辑部专用服务
作者专用服务
2013年西安市强制戒毒人员乙型肝炎病毒感染及疫苗接种状况调查
目的 调查西安市强制戒毒人员乙型肝炎(简称乙肝)病毒(HBV)感染现状及乙肝疫苗接种情况.方法 于月,对西安市某家强制戒毒所所内的545名强制戒毒人员进行问卷调查,采集静脉血3 ～5 ml,检测其乙肝表面抗原(HBsAg)、核心抗体(抗-HBc)和表面抗体(抗-HBs),比较不同特征调查对象HBV感染指标阳性率及疫苗接种率差异.结果 HBsAg、抗-HBc、抗-HBs的阳性率分别为29.4％(160/545)、60.0％(327/545)、56.1％(306/545),3项均为阴性者85名(15.6％).注射吸毒者HBsAg阳性率为40.0％(94/235),抗-HBc阳性率为65.5％(154/235),均高于非注射吸毒者[21.6％ (52/241)、58.5％(141/241)]和注射、非注射混用者[20.3％(14/69)、46.4％ (32/69)](x2值分别为23.52、9.02,P值均＜0.05).强制戒毒前1年内吸毒频次≥1次/d者HBsAg阳性率[30.6％ (153/500)]高于2～3次/周者[15.6％ (7/45)](x2=4.51,P＜0.05).乙肝疫苗接种率为11.7％ (64/545).小学以下文化程度调查对象的接种率[3.5％ (5/141)]低于高中以上[10.9％ (14/128)]和初中文化程度[16.3％ (45/276)](x2=26.61,P＜0.05).≥45岁组接种率[7.8％ (12/153)]低于＜30[15.9％ (21/132)]、30 ～44[11.9％ (31/260)]岁组(x2=30.36,P＜0.05).接种者抗-HBs阳性率[73.4％(47/64)]高于未接种者[53.8％ (259/481)](x2=8.81,P=0.003),其HBsAg阳性率[16.7％ (11/64)]低于未接种者[31.0％ (149/481)](x2=5.18,P=0.023).结论 西安市强制戒毒人员HBV感染状况较严重,乙肝疫苗接种率较低.
Abstract：
Objective To explore seroepidemiological status and vaccine coverage of hepatitis B among drug users in Xi'an.Methods 545 drug users in the Xi'an Compulsory Detoxification Center were asked to answer questionnaire and provide blood sample (3-5 ml) for test of HBsAg,anti-HBc and anti-HBs from March to June 2013.Totally,545 subjects were surveyed and tested.All of them effectively completed the survey.Results The positive rates of HBsAg,anti-HBc and anti-HBs were 29.4％ (160/545),60.0％ (327/545) and 56.1％ (306/545),respectively.Eighty five subjects (15.6％) were negative for all of the three markers.The prevalence of HBsAg and anti-HBc among injection drug users were 40.0％ (94/235) and 65.6％ (154/235),which was significantly higher than non-injection drug users' (21.6％ (52/241),58.5％ (141/241)) and mixed non-injection and injection drug users ((20.3％ (14/69),46.4％ (32/69)) (x2 =23.518 and 9.017,respectively,P ＜ 0.05).The HBsAg positive rate (30.6％ (153/500)) of subjects with more than once per day of drug using within one year was significantly higher than those who used drugs for 2-3 times per week (15.6％ (7/45))(x2 =4.51,P ＜ 0.05).Only 11.7％ (64/545) of drug users had a clear history of hepatitis B vaccination.The vaccination rate of subjects (3.5％ (5/141)) with primary education or below was significantly lower than those with high school (16.3％ (45/276)) (x2 =26.61,P ＜ 0.05).The vaccination rate of subjects (7.8％ (12/153)) over 45 years old was significantly lower than that of subjects below 30 years old (15.9％ (21/132)) and 30-44 years old (11.9％ (31/260)) (x2 =30.36,P ＜ 0.05).The vaccinees had a significantly higher positive rate of anti-HBs (73.4％ (47/64)) than those who without vaccination (53.8％ (259/481)) (x2 =8.81,P =0.003),but the positive rates of HBsAg (16.7％ (11/64))were lower than those who without vaccination (31.0％ (149/481)) (x2 =23.52 and 9.02, P ＞ 0.05).Conclusion The HBV infection status among drug users in Xi'an was in serious condition,while a low vaccination rate was also discovered among them.
Wei Xiaoli
You Lijuan
Kou Lingling
Li Hengxin
Zhuang Guihua
作者单位：
710061,西安交通大学公共卫生学院
710061,西安交通大学数学与统计学院
陕西省西安市疾病预防控制中心
年，卷(期)：
Keywords：
在线出版日期：
基金项目：
国家科技重大专项
本文读者也读过
相关检索词
万方数据知识服务平台--国家科技支撑计划资助项目（编号：2006BAH03B01）(C)北京万方数据股份有限公司
万方数据电子出版社百度拇指医生
&&&普通咨询
您的网络环境存在异常，
请输入验证码
验证码输入错误，请重新输入百度拇指医生
&&&普通咨询
您的网络环境存在异常，
请输入验证码
验证码输入错误，请重新输入百度拇指医生
&&&普通咨询
您的网络环境存在异常，
请输入验证码
验证码输入错误，请重新输入}