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4x+1.2x5=24.452-x=15
大娘很2_120
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4x+1.2x5=24.44x=24.4-6x=4.652-x=15－x＝15－52x＝37不懂欢迎追问^_^
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&nbsp&&nbsp&nbsp&&nbsp
-%2718-F-氟咪索硝唑(-%2718-F-FMISO)的自动化合成生物性能评价以及6-%5b-%2718-F%5d-L-DOPA的合成探索.pdf 91页
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1------------------------------ ThesisofMD’s
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此外，以3，4．二甲氧基氟苯为原料，分别采用非对称合成和对称合成来进行 6．【18F】．L-DOPA的冷合成探索。 成，合成时间约为45min，放化收率大于60％(衰变校正)，最大放化收率为75％。 所得18F．FMISO放射化学纯度大于98％并具有良好的稳定性。动物分布以及显像实
以明显显示出肿瘤位置。
利用非对称合成，反应混合物用显色剂进行鉴定，推测产品中6．氟．L．DOPA的 存在；利用对称合成，同样经显色剂进行鉴定，推测产品中6．氟．D，L．DOPA的存在， 但是由于产品极易氧化，未进一步分离。 低标记成本。利用改造后的合成模块，通过对反应条件的优化，可实现18F．FMISO 的快速自动化合成，并获得较高的放化收率。合成的18FMISO注射液可用于动物及 人体的乏氧组织研究。
对6．[18F】．L-DOPA的冷合成条件进行探讨，虽未成功分离到产品，但对今后的 研究奠定了基础。
2------------------------------
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