右腿股骨颈骨折手术费用出院后医院配的二种药:拜瑞妥和骨疏康颗粒,拜瑞妥一种吃完了,8号做的手术,8号复查,可

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拜瑞妥(利伐沙班片)是一种新型抗凝药物,可用于预防静脉血栓。目前传统的抗凝药物有普通肝素、低分子肝素和维生素K拮抗剂如华法林,利伐沙班与其它抗凝药物相比的优势表现在哪?以及使用注意事项有哪些?
拜瑞妥(利伐沙班片)与其它抗凝药物相比的优势表现在哪?
拜瑞妥(利伐沙班片)抗凝治疗的疗效及安全性已经得到临床试验的证实,累及了循证医学证据。普通肝素需静脉推注、低分子肝素需皮下注射,而华法林虽为口服制剂,但易受多种食物和药物的影响,需要抽血实验室检查密切监测INR;这些药物疗效确切,但使用均不方便。相对于肝素和华法林等传统抗凝药物相比,利伐沙班具有服用方便、起效快、无需进行凝血监测、安全性高等特点。
拜瑞妥(利伐沙班片)的适应症包括哪些?用法用量怎样?使用当中应该注意什么?
用于择期髋关节或膝关节置换手术成年患者,以预防静脉血栓形成(VTE)。
推荐剂量为口服利伐沙班10mg,每日1次。如伤口已止血,首次用药时间应于手术后6-10小时之间进行。治疗疗程长短依据每个患者发生静脉血栓栓塞事件的风险而定,即由患者所接受的骨科手术类型而定。对于接受髋关节大手术的患者,推荐一个治疗疗程为服药5周。对于接受膝关节大手术的患者,推荐一个治疗疗程为服药2周。如果发生漏服1次用药,患者应立即服用利伐沙班,并于次日继续每天服药1次。患者可以在进餐时服用利伐沙班,也可以单独服用。
由于拜瑞妥(利伐沙班片)的药效学性质,用药过量可能导致出血并发症。同时一些亚群的患者的出血风险较高,比如有肝损害和肾损害患者。治疗开始后,要对这些患者实施密切监测,观察是否有出血并发症征象。
对利伐沙班或片剂中任何辅料过敏的患者;有临床明显活动性出血的患者;具有凝血异常和临床相关出血风险的肝病患者;孕妇及哺乳期妇女都应该禁用。
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