<meta name="citation_abstract" content="Preeclampsia is a systemic syndrome that occurs in 5 to 8% of pregnancies and is a leading cause of maternal and neonatal morbidity and mortality. There are no clinically available tests that are well in selecting women who will develop preeclampsia. Purpose of the study was to combine standard biochemical and hematological markers at third trimester of pregnancy in assessing the risk of preeclampsia and to evaluate the use of additional generally available standard laboratory tests (in particular or in a group as a test panel), in prognosis of preeclampsia. This retrospective study was carried out on 113 patients with preeclampsia and a control group of 95 uncomplicated pregnancies. All subjects were in their 3-rd trimester of pregnancy and attended at Obstetric Department of the General Hospital Celje, Slovenia. Erythrocytes, leukocytes, thrombocytes, hemoglobin, hematocrit, AST, ALT, GGT, alkaline phosphatase, total bilirubin, urea, creatinine, uric acid, body mass index, parity, age, and blood type were evaluated to predict the occurrence of preeclampsia based on multivariate logistic regression model. ROC curve analysis pointed AUC of urate (0.856), creatinine (0.785) and urea (0.771) as the best preeclampsia predicting tests (p
Hrvatska znanstvena bibliografija (CROSBI)
Pregled bibliografske jedinice broj: 817279
Zbornik radova
?tefanovi?, M Deli?, Ratko
Biochemical and haematological parameters and their value in predicting preeclampsia
Clinical Chemistry and Laboratory Medicine
Dio CC ?asopisa:
4th Slovenian Congress of Clinical Chemistry
Mjesto i datum:
Portoro?, Slovenija, 28.9..2012.
Klju?ne rije?i:
Biochemical, haematological, parameters, preeclampsia
Preeclampsia is a systemic syndrome that occurs in 5 to 8% of pregnancies and is a leading cause of maternal and neonatal morbidity and mortality. There are no clinically available tests that are well in selecting women who will develop preeclampsia. Purpose of the study was to combine standard biochemical and hematological markers at third trimester of pregnancy in assessing the risk of preeclampsia and to evaluate the use of additional generally available standard laboratory tests (in particular or in a group as a test panel), in prognosis of preeclampsia. This retrospective study was carried out on 113 patients with preeclampsia and a control group of 95 uncomplicated pregnancies. All subjects were in their 3-rd trimester of pregnancy and attended at Obstetric Department of the General Hospital Celje, Slovenia. Erythrocytes, leukocytes, thrombocytes, hemoglobin, hematocrit, AST, ALT, GGT, alkaline phosphatase, total bilirubin, urea, creatinine, uric acid, body mass index, parity, age, and blood type were evaluated to predict the occurrence of preeclampsia based on multivariate logistic regression model. ROC curve analysis pointed AUC of urate (0.856), creatinine (0.785) and urea (0.771) as the best preeclampsia predicting tests (p<0, 001). Logistic regression model with uric acid and urea combined as a test panel, correctly classified 79.6% patients. Inclusion of additional four parameters (thrombocytes, hematocrit, aspartate aminotransferase and leukocytes) in this model, correctly classifiy 83.8% patients with preeclampsia. Blood pressure and proteinuria were not included in the model, because they served as diagnostic criteria to diagnose preeclampsia. Our findings show that when combining several standard laboratory tests (thrombocytes, hematocrit, aspartate aminotransferase and leukocytes) in a logistic regression model, it is possible to distinguish 84% of the preeclampsia cases. If coupled with current criteria (a new onset of hypertension and proteinuria after 20 weeks of gestation in previously normotensive woman), this test panel should identify even more cases. After validation in an independent population, proposed test panel could be used as a tool to help identify women at risk for developing preeclampsia.
Vrsta sudjelovanja:
Vrsta prezentacije u zborniku:
Vrsta recenzije:
Nema recenziju
Izvorni jezik:
Kategorija:
Znanstveni
Znanstvena podru?ja:
Klini?ke medicinske znanosti
Tiskani medij:
Upisao u CROSBI:
Mario ?tefanovi? (mario.stefanovic@kbcsm.hr), 20. Svi. 2016. u 18:45 sati本站已经通过实名认证，所有内容由徐列明大夫本人发表
胆囊切除1年后，alt,ast,akp,ggt升高
状态：就诊前
希望提供的帮助：
我这种情况可能是什么原因造成的 ，几项指标偏高对于怀孕会不会有影响。
所就诊医院科室：
四川华西医院 消化内科
成都市第一人民医院 肝胆外科
治疗情况：
医院科室：
成都市第一人民医院
治疗过程：胆囊切除
看来你需要作肝穿刺作病理检查，也许可以发现罕见的肝病。
状态：就诊前
化验单已上传,个人感觉是从前年早产后就恢复的不是很好 。
作肝穿刺吧！
1.扫码下载好大夫App
2.点击中的"免费咨询"描述病情
3.成功后，医生会在24小时之内回复
疾病名称：失眠多梦&&
希望得到的帮助：请医生给我一些治疗上的建议
病情描述：检查的肝功和三系统，但有事没看到医生，就想知道一下，这个化验结果是什么意思？求解答。
疾病名称：准备要小孩&&
希望得到的帮助：请医生给我一些治疗上的建议
病情描述：乏力，有点低血糖，无其他明显症状，睡眠不好
疾病名称：胆红素增高，谷丙转氨酶增高，两对半阴性&&
希望得到的帮助：需要做进一步检查吗？做哪些检查
病情描述：体检发现胆红素、谷丙转氨酶增高，乙肝两对半阴性
疾病名称：黄疸 淤胆型肝炎&&
希望得到的帮助：请医生给我一些治疗上的建议
病情描述：我父亲80岁，3月份开始出现食欲不振的现象，当时化验肝功稍高但基本正常。一个月前出现黄疸，且转氨酶高达1000多，于是在西苑医院住院治疗，一周后又转至地坛医院中西医结合科，现已治疗3周，但...
疾病名称：黄疸 淤胆型肝炎&&
希望得到的帮助：请医生给我一些治疗上的建议
病情描述：我父亲80岁，3月份开始出现食欲不振的现象，当时化验肝功稍高但基本正常。一个月前出现黄疸，且转氨酶高达1000多，于是在西苑医院住院治疗，一周后又转至地坛医院中西医结合科，现已治疗3周，但...
投诉类型：
投诉说明：（200个汉字以内）
徐列明大夫的信息
各种慢性肝病、肝硬化和脂肪肝
徐列明，男，主任医师，教授，曙光医院肝硬化专科主任，擅长治疗各种慢性肝病、肝硬化和脂肪肝。
徐列明大夫的电话咨询
90%当天通话，沟通充分!
中医肝病科可通话专家
北京中医医院
江苏省中医院
肝病中心（感染科）
北京佑安医院
中西医肝病科
副主任医师
北京中医医院
上海曙光医院东院
上海曙光医院东院
北京地坛医院
中西医结合肝病科胆囊急性炎症切除术后50天，不发烧，不恶心，化验ALT509，AST371，GGT301，总胆红素_百度知道
胆囊急性炎症切除术后50天，不发烧，不恶心，化验ALT509，AST371，GGT301，总胆红素
不恶心，碱性磷酸酶319，部分显示不清。核磁报告胆道系统扩张，化验ALT509，AST371.9，直接胆红素11，不发烧，总胆红素22,胆总管下段变细信号不均胆囊急性炎症切除术后50天，GGT301，胰腺信号不均 标签，胰管略增宽
我有更好的答案
胆总管有梗阻？可能造成胰腺病变。
你想问什么
我想问这是什么疾病？
胆管循环不畅
怎么治疗啊？
其他类似问题
为您推荐：
等待您来回答
下载知道APP
随时随地咨询
出门在外也不愁}